Echocardiographic features of cardiac damage caused by hypereosinophilic syndrome / 西安交通大学学报(医学版)

ABSTRACT

Objective: Hypereosinophilic syndrome (HES) is a hematological disorder that may involve multiple organs, especially the heart as the targeting organ, and is the most important cause of death among patients. This paper summarizes the clinical and echocardiographic results of patients diagnosed with HES so as to provide an accurate and feasible method for early detection and timely treatment of the disease. Methods: We retrospectively analyzed the clinical data of five HES patients who came to the Department of Cardiology, Xi'an Jiaotong University, from 2004 to 2014 with the purpose of finding out the common and specific manifestations in transthoracic echo imaging. Results: There were five patients diagnosed with HES, with four cases of idiopathic HES and one of secondary HES after parasitic infection. Atrial enlargement was detected in the five patients, including four cases with double atria expansion and two cases with ventricular dilatation. Endocardial thickening was observed in all the patients with thrombosis, including four cases of thrombus detected in the double chambers' apex of and one case of thrombus only in the left ventricular apex. Changes of the valves and the pericardium were also shown in the transthoracic echocardiographic images and might be the characteristic features. Conclusion: Cardiac damage caused by HES is the main cause of death in the patients. Echocardiography can accurately show characteristic changes and provide help for early detection and correct treatment.