Role of exosomes in tumor angiogenesis / 解剖学报

ABSTRACT

Exosomes are vesicle structures containing a variety of proteins, mRNA and Micro RNA and other important signaling molecules, which can participate in the exchange of materials and information between cells, thus affecting the physiological functions of cells. Tumor growth and metastasis depend on adequate angiogenesis and blood supply. More and more studies have confirmed that tumor drived exosomes are involved in promoting tumor angiogenesis. This article reviews how exosomes drive angiogenesis to add new options for improving existing antiangiogenic therapies.