Insulin autoimmune syndrome associated with alpha-lipoic acid in a young woman with no concomitant disease / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 115-118, 2017.
Article
Dans Coréen
| WPRIM
| ID: wpr-84527
ABSTRACT
Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia, extremely high serum insulin levels, and high titers of autoantibodies against endogenous insulin, in the absence of exogenous insulin injection. IAS often occurs following exposure to sulfhydryl-containing drugs, including alpha-lipoic acid (ALA). A 30-year-old woman without diabetes visited our outpatient clinic with recurrent hypoglycemia. She had been taken ALA for weight reduction since 3 weeks ago. Further hypoglycemia work up revealed very high insulin levels, C-Peptide levels and positive insulin antibodies. And conventional imaging examinations were negative for insulinoma or other pancreatic tumors. Finally, the diagnosis of Insulin autoimmune syndrome (IAS) was made. Following the cessation of ALA, hypoglycemia improved, with no medication, and the patient experienced no further hypoglycemic attacks over the next month. The use of ALA as a nutritional supplement is increasing. We report a case of IAS associated with ALA in a non-diabetic patient.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Autoanticorps
/
Peptide C
/
Perte de poids
/
Acide lipoïque
/
Diagnostic
/
Établissements de soins ambulatoires
/
Hypoglycémie
/
Insuline
/
Anticorps anti-insuline
/
Insulinome
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Coréen
Texte intégral:
Yeungnam University Journal of Medicine
Année:
2017
Type:
Article
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