Stereotactic ablation radiotherapy for early stage non-small cell lung cancer: Progress and challenge / 肿瘤

ABSTRACT

With the continuous development of diagnostic technology, the detection rate of early-stage non-small cell lung cancer (NSCLC) is increasing. For a long time, the standard treatment for early-stage lung cancer is lobectomy combined with lymph node dissection or sublobectomy. Since the emergence of stereotactic body radiotherapy (SBRT), it has long been a preferred alternative for early-stage NSCLC patients who cannot tolerate surgery or because of other reasons. Recent studies have shown that for early-stage NSCLC patients who are operable, SBRT can achieve the same or even better effect as surgery. However, there is still a lot of controversies in the medical community on the application of SBRT to the early-stage NSCLC. How to choose the early-stage NSCLC population that can benefit most from the SBRT treatment is the current research focus. Several ongoing prospective randomized controlled studies may provide an answer.