Advances in chemotherapy combined with immunotherapy for advanced lung cancer / 肿瘤

ABSTRACT

Recent studies have showed that the single immunotherapy could get excellent therapeutic effect on lung cancer. A large number of basic and clinical studies have showed that the combination of chemotherapy and immunotherapy may have better efficacy than single therapy. Chemotherapy may stimulate the innate immune response and the acquired immune cells directly, block the immune suppressive pathways which promote tumor progression, enhance tumor cell antigenicity or immunogenicity, or enhance the sensitivity of immune effect. At present, the clinical research on combination of chemotherapy and immunotherapy is in progress, but the side effects should not be ignored.