Progress in radiotherapy for the treatment of oligometastasis / 肿瘤

ABSTRACT

Tumor metastasis is an evolution process from local lesion to systemic diseases, in which there are many intermediate states. Oligometastasis is a milder stage of tumor biological invasiveness, and also a state model in the process of tumor metastasis. With the limited less metastases, oligometastasis is a transitional stage between local primary tumor and extensive distant metastasis, and does not have the genetic tendency of systemic spread. Local therapy is mainly used for oligometastasis. Due to the development of radiation and imaging technology, the radiotherapy has gradually become an important treatment. Especially, the stereotactic radiotherapy has been proved to be safe and effective, with less adverse reactions, high local control rate and long-term survival. Despite of its good results and effects, the stereotactic radiotherapy is still facing various clinical challenges, especially in the selection criteria of candidate patients and therapeutic strategies. This paper reviews the clinical progress in tumor oligometastasis and the application of radiation therapy in the treatment of tumor oligometastasis, in order to provide a better treatment for the patients with oligometastasis.