The clinical features of breast cancer in young patients / 肿瘤

ABSTRACT

Objective: To explore and compare the clinical and pathologic features of breast cancer between the young women ( 0.05). The proportion of Luminal B was higher in the young patients than that in the elder patients. The median survial time was not significantly different between the young and the elder patients (58.2 vs 45.8 months, P > 0.05). The univariate analysis revealed that PR-negative and lymph node and distant metastases were associated with lower five-year survival rate in young patients (P < 0.05). The multivariate analysis revealed that lymph node and distant metastases were independent prognostic factors in young patients (P < 0.05). Conclusion: Young patients with breast cancer have more poor prognostic factors than the elders, such as later stages of tumor size and lymph node, more proportion of type Luminal B, and higher rate of breast-conserving radical surgery, but the overall survival between the young and the elder patients had no significant difference.