A new lactone from Alternaria sp. IS275, an endophytic fungus of Ligusticum chuanxiong / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 4859-4862, 2019.
Article
Dans Chinois
| WPRIM
| ID: wpr-850760
ABSTRACT
Objective:
To study the chemical constituents of metabolites of Alternaria sp. IS275, an endophytic fungus isolated from Ligusticum chuanxiong.Methods:
The extraction fraction of ethyl acetate from endophytic fungi fermentation broth of L. chuanxiong were isolated and purified by silica gel, Sephadex LH-20, reversed phase medium pressure chromatography, preparative TLC, and semi-preparative RP-HPLC. The structure of the separated chemical constituent was elucidated by modern spectroscopy technology.Results:
A new lactone compound (+)-4,11-dihydroxy-2-dodecene-5-lactone was isolated from the ethyl acetate fraction of the metabolite of Alternaria sp. IS275, an endophytic fungus of L. chuanxiong.Conclusion:
Compound 1 is a new lactone compound, named ligualterlide A.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Traditional and Herbal Drugs
Année:
2019
Type:
Article
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