A new norlignan from fruiting bodies of Amauroderma rude / 中草药

ABSTRACT

Objective For the purpose of finding new bioactive compounds from natural resources, the phytochemical investigation on the fruiting bodies of Amauroderma rude was carried out. Methods The chemical constituents from A. rude were isolated by various technologies, such as silica gel, Sephadex LH-20, MCI-gel resin, and high performance liquid chromatography. The isolated compounds were elucidated by spectroscopic methods, including extensive 1D, 2D NMR, and ESI-MS techniques. Results Three compounds (1-3) including a new norlignan, were isolated from this mushroom. Their structures were identified as 4-ethyoyl-E-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2-one (1), esculetin (2), and caffeic acid (3). Conclusion Compound 1 is a new compound isolated from this fungus, which is identified as amauroderin A.