Screening of transdermal enhancer of naringenin in Premna fulva extract / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 3366-3369, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-852592
ABSTRACT
Objective:
To screen the best transdermal enhancers of naringenin in Premna fulva extract.Methods:
Using abdominal skin of rats as experimental barrier, the in vitro percutaneous absorption experiment was established by modified Franz diffusion cell method. The cumulative infiltration and permeation rate of naringenin in three different penetration enhancers were determined by HPLC.Results:
The borneol, menthol, and azone could enhance transdermal absorption of naringenin in different degree. Several penetration enhancers were increased in the following order borneol > menthol > azone. The average percutaneous rate of naringenin was 0.136 8 mg/(cm2∙h), using 5% borneol as penetration enhancer.Conclusion:
The 5% borneol is an effective transdermal enhancer for naringenin in P. fulva extract.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Etude diagnostique
/
Étude de dépistage
langue:
Chinois
Texte intégral:
Chinese Traditional and Herbal Drugs
Année:
2017
Type:
Article
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