Chemical constituents of Patrinia villosa / 中草药

ABSTRACT

Objective: To study the chemical constituents of Patrinia villosa. Methods: Compounds were isolated by a combination of various chromatographic techniques including column chromatography over macroporous resin, Sephadex LH-20, and reversed-phase HPLC. Their structures were elucidated by physiochemical property and spectral analysis. Results: Fourteen compounds were isolated and identified as isololiolide (1), citroside A (2), grasshopper kectone (3), (E)-4-Hydroxy-3,3,5-trimethy1-4- (3-oxobut-1-en-1-yl)-cyclohexan-1-one (4), bluemenol A (5), pubinernoid A (6), robinin (7), puerarin (8), 5-(1'-hydroxyethyl)-methyl nicotinate (9), 2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-propance-1,3-diol (10), 1-O-(β-D-glucosyl)-2-[2-methoxy-4-(3-hydroxypropyl)- phenoxy]-propan-3-ol (11), dihydrosinapyl alcohol (12), 3,5-dimethoxyl-4-hydroxyl-phenylpropanol-9-O-β-D-glucopyranoside (13), and 2-phenylethy-α-L-arabinopyranosyl-(1″→6')-β-D-glucopyranoside (14). Conclusion: All compounds are isolated from the plants of Patrinia Juss. for the first time.