Chemical constituents of Salvia plebeia / 中草药

ABSTRACT

Objective: To study the chemical constituents from the herb of Salvia plebeian. Methods: The constituents were isolated and purified by silica gel, Sephadex LH-20, and ODS column chromatography, and preparative TLC. The structures of the isolated compounds were elucidated by spectroscopic analysis and physicochemical properties. Results: Eleven compounds were isolated and purified from the ethanol extract of S. plebeia. They were identified as 5,6-dihydroxy-7,4'-dimethoxyflavone (1), 5,6,3'-trihydroxy-7,4'-dimethoxyflavone (2), nepetin (3), homoplantaginin (4), apigenin (5), cirsiliol (6), 6-methoxynaringenin (7), emodin (8), maslinic acid (9), isorosmanol (10), and (-)-epiloliolide (11). Conclusion: Among them, compound 11 is isolated from the plants of Salvia L. firstly, and compounds 1, 2, 6, 9, and 10 are isolated from S. plebeian for the first time.