Nootropic effect of gensenosides Rg1 and Rb1 and their metabolites / 中草药

ABSTRACT

As the main active ingredients of ginseng, ginsenosides have many pharmacologic effects, and the nootropic effects are the important pharmacologic action of ginsenosides. Among all of the ginsenosides, the contents of ginsenosides Rg1 and Rb1 are the highest. The nootropic effects of ginsenosides Rg Rb1, and their metabolites are summarized in this paper following four aspects the effects of ginsenoside Rg1 and Rb1 on the animal behaviors, their effects on different brain regions in rodents, the effects on neurotransmitters, and their effects on signaling pathway on learning and memory. The nootropic effects of their metabolites are also mentioned.