Study on chemical constituents of Daphne gracilis / 中草药

ABSTRACT

Objective: To investigate the chemical constituents of Daphne gracilis. Methods: The constituents were separated and purified by chromatographic methods and their structures were elucidated by spectroscopic methods and chemical analyses. Results: Fifteen compounds were obtained and identified as β-sitosterol (1), friedelin (2), stigmast-4-ene-3-one (3), stigmast-4-ene-3, 6-dione (4), lupeol (5), stigmasterol (6), 1, 3-distearate glycerol (7), glycerin-docosanate (8), octadecanol (9), phytol (10), dehydrodiconiferyl alcohol (11), epoxyconiferyl alcohol (12), oleodaphnone (13), 14-gingerol (14), and matairesinol (15). Conclusion: All the compounds are isolated from the plants of D. gracilis for the first time. Among them, compound 2-4, 7-9, 11, 12, and 14 are isolated from the plants in Daphne L. for the first time; Compounds 11, 12, and 14 are isolated from the plants of family Thymelaeaceae for the first time.