Chemical constituents from radix and rhizome of Myrsine stolonifera / 中草药

ABSTRACT

Objective: To study the chemical constituents from the radix and rhizome of Myrsine stolonifera. Methods: The chemical constituents were isolated and purified by D101 macroporous adsorption resin, silica gel, and Sephadex LH-20 column chromatography. The structures of the isolated compounds were identified on the basis of physicochemical properties and spectroscopic methods including 1H-NMR, 13C-NMR, and MS spectra. Results: Eleven compounds were identified as askaempferol (1), dihydrokaempferol (2), quercetin (3), 5, 7, 4'-trihydroxyisoflavone (4), chrysoeriol (5), quercetin-7-O-α-D-glucoside (6), (-)- epicatechin (7), 3, 5-dimethoxy-benzylalcohol-4-O-β-D-glucopyranoside (8), 2, 6-dimethoxy-4-hydroxyphenol-1-O-β-D- glucopyranoside (9), syringing (10), and (+)-lyoniresinol3α-O-β-D-glucopyranoside (11). Conclusion: Compounds 2, 4-11 are all isolated from the plants of Myrsine Linn. for the first time, and compounds 1-11 are all isolated from this plant for the first time.