Chemical constituents in Lepidium meyenii cultivated in Jilin / 中草药

ABSTRACT

Objective: To study the chemical constituents from the dried rhizome of Lepidium meyenii (Maca) cultivated in Jilin. Methods: The chemical constituents were isolated and purified with macroreticular resin, silica gel, ODS column chromatography, preparation HPLC, etc. The structures of the compounds were identified by physicochemical properties and various spectroscopic methods. Results: Thirteen compounds were isolated as N-methyl-3-hydroxy-benzeneacetamide (1), N-benzyloctadecanamide (2), benzeneacetamide (3), benzylamine (4), 3-methoxyphenylacetic acid (5), phenylacetic acid (6), 4-hydroxy-3-methoxybenzoic acid (7), nicotinic acid (8), 3, 4-dihydroxy-benzoic acid methyl ester (9), adenosine (10), L-valine (11), daueosterol (12), and β-sitosterol (13). Conclusion: Compound 1 is identifled as a new natural compound, and compounds 3-6 and 9-12 are obtained from L. meyenii for the first time.