Effects of Xueshuantong injection on platelet aggregation in rabbits in vitro / 中草药

ABSTRACT

Objective: To study the effects of Xueshuantong injection (lyophilized, main component of Panax Notoginsenosidum, total content of 95%) on platelet aggregation induced by adenosine diphosphate (ADP), arachidonic acid (AA), and platelet-activating factor (PAF) in rabbits. Methods: Using the Born method, the platelet aggregation induced by ADP, AA, and PAF was detected. Results: Compared with the control group, Xueshuantong injection (7.2 and 14.4 mg/mL) could significantly inhibit the platelet aggregation rate induced by ADP, AA, and PAF (P < 0.01), Xueshuantong injection (3.6 mg/mL) could significantly inhibit the platelet aggregation rate induced by ADP (P < 0.01). Conclusion: Xueshuantong injection could inhibit the in vitro platelet aggregation of rabbits.