Chemical constituents from charred Sanguisorbae Radix / 中草药

ABSTRACT

Objective: To study the chemical constituents from charred Sanguisorbae Radix. Methods: The compounds were isolated and purified by column chromatography and their structures were identified on the basis of physicochemical properties and spectral analysis. Results: Five compounds were isolated and identified as 3β-hydroxy-28-norurs-17, 19, 21-trien (1), 3β-hydroxy-28- norurs-12, 17-dien (2), 3β-[(α-L-arabinofuranosyl) oxy]-28-norurs-12, 17-dien 3β, 19α-dihydroxyurs-13(18)-en-28-oic acid (3), 3β- [(α-L-arabinopyranosyl)oxy]-28-norurs-12, 17-dien (4), and pomolic acid (5). Conclusion: The compounds 1, 3, and 4 are novel compounds which belong to triterpenoids and triterpenoid saponins, named sanguisorbigenin Z, sanguisorbin Y1, and sanguisorbin Y2, respectively.