Development of senolytics for selectively elimination of senescent cells / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 1333-1337, 2019.
Article
Dans Chinois
| WPRIM
| ID: wpr-857113
ABSTRACT
Aging is the primary risk factor for many of the most common chronic diseases. The association of cellular senescence with aging-associated conditions has gaining increasing attention. There is now considerable evidence that senescent cell accumulation is an underlying mechanism of aging and age-related diseases. Senescent cells have been emerging as a target for new therapeutic strategies against aging-related pathology. Herein, we review the evidence that cellular senescence drives age-related deterioration and senolytics produce beneficial effect by selective elimination of senescent cells.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Facteurs de risque
langue:
Chinois
Texte intégral:
Chinese Pharmacological Bulletin
Année:
2019
Type:
Article
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