Progress in the Industrialization of Sustained-release Microsphere / 中国药学杂志

ABSTRACT

Recently, drug-loading microspheres prepared from biodegradable polymers have attracted great attentions. It is a hot topic in the research of pharmaceutical preparations because it can be used to control release of the drug. The selection of suitable polymer materials and production technology are the key factors for preparing sustained release microspheres. With the launching of many control release microspheres, the technology has been developed into a mature technology, and it has been shown to be controllable and industrialized. This paper mainly introduces the industrialized production technology of microspheres and some new technologies for preparing microspheres, as well as the drugs that have been marketed.