Research Progress of Receptors of Plant Polysaccharides / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 1766-1772, 2019.
Article
Dans Chinois
| WPRIM
| ID: wpr-857867
ABSTRACT
Receptors of plant polysaccharides and their signaling pathways have become a hotspot of polysaccharide activity research. As immunomodulators, polysaccharides have attracted much attention due to their immunomodulatory effects mediated by cell surface receptors. Polysaccharide receptors mainly include C-type lectin receptor family, mannose receptor family (MR), Toll-like receptor family (TLR), complement receptor 3 (CR3), scavenger receptor and so on, and these receptors play an important role in the recognition between polysaccharides and cells, which is closely related to polysaccharides activities, such as enhancing cellular immune function, regulating the secretion of cytokines, having immunomodulatory and antineoplastic effects. In this paper, polysaccharide receptors types, biological functions and signal transduction pathways are reviewed, it will be helpful to elucidate the pharmacological activity mechanism of plant polysaccharides and provide theoretical reference for the comprehensive development of polysaccharide drugs.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Pharmaceutical Journal
Année:
2019
Type:
Article
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