Advances in research of small molecule tyrosine kinase inhibitors for targeted cancer therapy / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 165-171, 2016.
Article
Dans Chinois
| WPRIM
| ID: wpr-859215
ABSTRACT
To review the research progress of small molecule tyrosine kinase inhibitors (TKIs). Literatures on tyrosine kinase inhibitors which have already been successfully marketed or are in development were sorted and summarized according to the targets and related cancers. Through binding to catalytic domain of intracellular tyrosine kinase, small molecule TKIs inhibit the catalytic activity specifically and block cell proliferation signals, and some of them have already been used in cancer therapy or are in different stages of clinical development, showing good prospects.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Pharmaceutical Journal
Année:
2016
Type:
Article
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