Comparison evaluation of statistical analysis methods for inter-laboratory comparison statistical analysis methods / 中国药学杂志

ABSTRACT

OBJECTIVE: To identify the characteristics and application conditions of currently statistical methods for inter-laboratory comparison and proficiency testing results analysis in drug control, combining with the international standards and practical application. METHODS: Based on the ISO/IEC 17043-GB/T28043, start beging with the definition of outliers, the methods currently used in inter-laboratory comparison and proficiency testing results analysis both at home and abroad methods were summarized and compared according to the ISO/IEC 17043-GB/T28043, with focused on the testing the stability and repeatability of laboratory testing proficiency. The most-used stastical methods of mter-laboratory comparison and proficiency testing during present domestic and international drug testing was sumarrized and contratively analyzed. RESULTS: The application conditions of different methods good contrast were providedidentified application condition of methods. CONCLUSION: Robust Z-score has more advantages in current stage of inter-laboratory comparison and proficiency testing results analysis.