Study on chemical constituents of Alocasia macrorrhiza (L.) Schott / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Alocasia macrorrhiza (L.) Schott. METHODS: Chemical constituents were extracted by organic solvents, isolated and purified by chromatographic techniques with silica gel, polyamide, ODS, Sephadex LH-20, semi-preparative HPLC and recrystallization. Their structures were identified on the basis of physicochemical properties and spectral data analyses of MS and NMR, et al. RESULTS: Nine compounds were isolated from its rhizoma and identified as glycosmisic acid (1), N-trans-feruloyltyramine(2), grossamide(3), protocatechuic acid(4), borneol acetate(5), vanillic acid(6), methyl 4-hydroxybenzoate(7), β-daucosterol(8), and β-sitosterol(9). CONCLUSION: Compounds 1-9 were isolated from Alocasia macrorrhiza for the first time.