Determination of 192 pesticides in flos lonicerae by gas chromatography-mass spectrometry / 中国药学杂志

ABSTRACT

OBJECTIVE: To establish a gas chromatography-mass spectrometry (GC-MS) method for detecting 192 pesticides in flos lonicerae. Several bathes of flos lonicerae have been determined in order to find out the current status of pesticide residues in flos lonicerae. METHODS: The samples were extracted with acetone, and cleaned-up by the combination of gel permeation chromatography (GPC) and solid-phase extraction (SPE), and determined by GC-MS. RESULTS: The recoveries of most pesticides ranged from 70% to 110% with relative standard deviations (RSDs) ≤15%. The limits of determination were below 0.01 mg·kg-1. CONCLUSION: This method is sensitive, accurate, and can be used for the determination of multi-residual pesticides in flos lonicerae. Copyright 2012 by the Chinese Pharmaceutical Association.