3D arterial spin labeling and diffusion tensor imaging combined with conventional MRI in differential diagnosis of hemangiopericytoma and angiomatous meningioma / 中国医学影像技术

ABSTRACT

Objective:To explore the value of 3D arterial spin labeling (3D ASL) and diffusion tensor imaging (DTI) combined with conventional MRI in differential diagnosis of hemangiopericytoma (HPC) and angiomatous meningioma (AM). Methods: Data of 15 cases of HPC (HPC group) and 11 cases of AM (AM group) confirmed by postoperative pathology were retrospectively analyzed. The clinical data, MRI (including plain and enhanced scanning, DTI and 3D ASL) findings and functional imaging parameters were analyzed between two groups. Results: The mean cerebral blood flow (CBF) and fractional anisotropy (FA) in HPC group were all lower than those in AM group (t=-8.99, P<0.01; t=-3.66, P<0.01), and the apparent diffusion coefficient (ADC) in HPC group was higher than that in AM group (t=2.61, P=0.02). CBF of high perfusion area and low perfusion area were also lower in HPC group than that in AM group (t=-15.13, P<0.01; t=-8.30, P<0.01). The mean age of onset was lower in HPC group than in AM group (t=-2.39, P=0.02). Lobulated sign (χ2=9.09, P<0.01), tumor cystic necrosis (χ2=9.38, P<0.01), mainly iso-hyperintense signals on T1WI (χ2=27.78, P<0.01) and iso-hyperintense signals on T2WI (χ2=16.33, P<0.01), mild extent of peritumoral edema (χ2=19.25, P<0.01), dilated blood flow void (χ2=9.02, P=0.01), narrow base with dura mater(χ2=28.54, P<0.01) and seldom on dural tail sign (χ2=25.00, P<0.01) were more common in HPC group than in AM group. No significant difference of patients' gender was found between HPC group and AM group (χ2=1.69, P=0.19). Conclusion: There were some differences of MRI features and functional imaging parameters between HPC and AM, which could provide references for differential diagnosis of these two diseases.