Single and combination of virtual touch tissue imaging quantification technique and mammography in diagnosis of benign and malignant breast lesions / 中国医学影像技术

ABSTRACT

Objective: To investigate the value of single and combination of virtual touch tissue imaging quantification (VTIQ) technique and mammography in diagnosis of benign and malignant breast lesions. Methods: VTIQ and mammography were performed on 99 patients (110 breast lesions).The mean value of shear wave velocity (SWVmean) of breast lesions were obtained. Mammographic classification of breast lesions was obtained with breast imaging reporting and data system (BI-RADS). Taken pathology as gold standard, the ROC curve was used to evaluate the diagnostic efficacy of SWVmean, mammography and the combination of these two methods. The differences of AUC among single and combined VTIQ technique and mammography in diagnosis of benign and malignant breast lesions were compared. Results: SWVmean of benign breast lesions was (3.03±0.78) m/s, of malignant ones was (5.61±2.11) m/s (P<0.001). The cutoff value of SWVmean in diagnosis of benign and malignant breast lesions was 3.93 m/s, and of mammography was BI-RADS 4B. AUC of VTIQ, mammography and combination was 0.870, 0.749 and 0.873, respectively. The differences of AUC between VTIQ technique and mammography, combination and mammography were statistically significant (P=0.036, 0.015), while of AUC between the combination and VTIQ technique was not statistically significant (P=0.908). Conclusion: Combination of VTIQ technique and mammography has high efficacy in diagnosis of benign and malignant breast lesions.