Radioactive seed localization and wire-guided localization in excision of non-palpable breast lesions / 中国医学影像技术

ABSTRACT

Objective: To compare the efficacy of radioactive seed localization (RSL) and wire-guided localization (WL) for intraoperative localization of non-palpable breast lesions, and to observe the application value of RSL. Methods Totally 72 women with non-palpable breast lesions who would underwent breast-conserving surgery were enrolled and divided into RSL group (n=34) and WL group (n=38). WL was performed at the same day as surgical excision, while RSL was performed within 5 days before the surgery. The precision rate of location, the rates of tumor-free margin and re-excision, as well as the localization-related complications were compared between the two groups. Results: All lesions were precisely located and completely removed. The tumor-free margin rate and the re-excision rate of RSL was 91.18%(31/34) and 5.88%(2/34), while of WL was 65.79%(25/38) and 28.95%(11/38), respectively. There were significant differences between the two groups (both P<0.01). In WL group, 2 cases occurred wire shifting, 1 case had the vagus nerve response, while no localization-related complication occurred in RLS group. Conclusion: Both RSL and WL can be used for accurate localization and guided-resection of non-palpable breast lesions. Compared with WL, positioning of RSL is not affected by operation time, which has higher tumor-free margin rate and lower re-excision rate.