Clinical Analysis of Biliary Drainage of Biliary Obstruction Diseases Under Endoscopic Retrograde Cholangiopancreatography / 胃肠病学

ABSTRACT

Background: There are many biliary drainage methods for the treatment of biliary obstruction diseases, and the application of endoscopic biliary drainage has been increased gradually. Aims: To compare the effect and complications of different endoscopic biliary drainage for the treatment of biliary obstruction diseases. Methods: A total of 75 patients with biliary obstruction diseases received endoscopic retrograde cholangiopancreatography (ERCP) from February 2012 to December 2017 at the People's Hospital of Xuancheng City were enrolled. The patients were divided into nasobiliary drainage group and biliary stenting group. The success rate, effect, complication of drainage were compared between the two groups, and the cause of biliary re-obstruction after ERCP was analyzed. Results: Before treatment, TBIL, DBIL levels were significantly increased in biliary stenting group than in nasobiliary drainage group (P<0.01). After the treatment, no significant difference in success rate of drainage was found between the two groups. No significant differences in TBIL, DBIL before and after treatment were found between the two groups. After the treatment, ALT, AST, GGT was significantly decreased, and AMS was significantly increased in nasobiliary drainage group (P<0.05); while ALT, GGT, AMS were significantly decreased in biliary stenting group (P<0.05). No significantly difference in incidence of complication was found between the two groups. The causes of biliary re-obstruction after ERCP were mainly bile mud or sedimentary calculus, massive stone, tumor invasion. Conclusions: The nasobiliary drainage and biliary stenting drainage can both improve liver function, and relieve the clinical symptoms of biliary obstruction. No significant difference in drainage effect and complication are found between the two drainage methods.