MSCT evaluation on dynamic changes of aortic annulus during cardiac cycle / 中国介入影像与治疗学

ABSTRACT

Objective: To explore the dynamism of aortic annulus (AA) during cardiac cycle and the correlation with calcification with MSCT. Methods A total of 69 aortic stenosis patients (AS group) and 69 controls (normal control group) underwent MSCT. Dimensions of AA were assessed on both systolic and diastolic phase. For each phase, the long diameter, short diameter, area and perimeter of AA were measured, respectively. The features of annular dimension change and the relationship with calcium score were analyzed. Finally, the differences of dynamic of AA in different calcification grades were compared. Results The mean annular dimensions were significantly larger during systole than diastole (all P0.05). In AS group, the perimeter-derived diameter (DP) of AA was significantly larger than the area-derived diameter (DA) in both systolic and diastolic phase (P<0.001). The change rate of AA area was significantly higher than change rate of perimeter (P<0.001) during cardiac cycle. There were negative correlation between the calcium score of AA and the change of DA and Dp (r=-0.264, -0.302, P<0.05). The dynamic of AA had significant difference among different calcification grades (P<0.05). Conclusion: The morphology and structure of AA significantly changed during cardiac cycle, and the dynamic change of AA with severe calcification significantly reduced. Systolic multiparameter measurement might provide accurate anatomical data for transcatheter aortic valve replacement.