Balanced steady-state free precession MRA for diagnosing renal artery stenosis: Meta-analysis / 中国介入影像与治疗学

ABSTRACT

Objective" To investigate the value of balanced steady-state free precession (B-SSFP) MRA for diagnosing renal artery stenosis (RAS) with Meta-analysis. Methods PubMed, EMbase and Cochrane Library databases were searched. English studies assessed B-SSFP MRA diagnostic performance in RAS patients were reviewed. Quality assessment was conducted by adopting the Quality Assessment of Diagnostic Accuracy Studies-2 checklist. Statistical analysis was adopted using the software of Meta Disc 1.4 and Stata 12.0. The summary ROC (SROC) curve was drawn, and pooled AUC, sensitivity, specificity, diagnostic odds ratio were calculated. Results A total of 12 articles including 21 results were enrolled, which had highly heterogeneous by using random effects models. In B-SSFP diagnosing RAS, meta-analysis showed the pooled sensitivity was 0.85 (95%CI [0.81, 0.88], I2=56.8%) and pooled specificity was 0.96 (95% CI [0.95, 0.97], I2=85.3%), the area under the SROC curve was 0.964 4, the pooled diagnostic odds ratio was 137.94 (95%CI [84.75, 224.50]). Regression analysis showed that heterogeneity may be derived from the year of publication (P=0.038). Conclusion: B-SSFP MRA is accurate and reliable for diagnosing RAS, and may be the first choice in patients with renal insufficiency.