The Effect of Spinal Cord Injury on Pituitary-Testicular Hormone Axis in Rats / 대한비뇨기과학회지
Korean Journal of Urology
;
: 947-951, 1998.
Article
Dans Coréen
| WPRIM
| ID: wpr-86302
ABSTRACT
PURPOSE:
To investigate the effect of spinal cord injury(SCI) on male reproductive function, we evaluated changes of pituitary-testicular hormonal level at various time intervals in spinal cord injured rats. MATERIALS ANDMETHODS:
SCI was produced in 30 sexually mature Sprague-Dawley rats by T10 spinal cord transection. 20 controls received similar surgery without transection. Testosterone concentrations in the serum and testis, serum levels of follicle-stimulating hormone(FSH) and leutenizing hormone(LH) were measured with radioimmunoassay. Two way analysis of variance(ANOVA) was performed.RESULTS:
Testosterone levels in the serum and testis were lower at 2 weeks after injury than in controls, but others were not. Serum levels of FSH and LH were similar in both group.CONCLUSIONS:
Spinal cord injury in rats induced impairment of testosterone production in testis at 2 weeks.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Spermatogenèse
/
Moelle spinale
/
Traumatismes de la moelle épinière
/
Axis
/
Testicule
/
Testostérone
/
Dosage radioimmunologique
/
Rat Sprague-Dawley
Limites du sujet:
Animaux
/
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Korean Journal of Urology
Année:
1998
Type:
Article
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