A case of lupus nephritis with IVC and bilateral renal vein thrombosis / 대한내과학회지

ABSTRACT

Renal vein and inferior vena cava thrombosis are possible complications of nephrotic syndrome related to either primary glomerulonephritis or glomerulonephritis associated with systemic disease. However, renal vein and inferior vena cava thrombosis associated with systemic lupus erythematosus are rare. We experienced a case of bilateral renal vein and inferior vena cava thrombosis associated with systemic lupus erythematosus. A previously healthy 21-year-old female developed sudden flank pain without edema. Abdominal computed tomography (CT) showed bilateral renal vein and inferior vena cava thrombosis. She was diagnosed with systemic lupus erythematosus with nephrotic syndrome based on the clinical manifestations and laboratory findings. After anticoagulation therapy with heparin and insertion of an inferior vena cava filter, the thrombus improved markedly. There is a possibility of renal vein and inferior vena cava thrombosis in the clinical course of nephrotic syndrome caused by lupus nephritis.