Mechanisms and potential therapeutic targets for coronary collateral growth / 中华老年医学杂志

ABSTRACT

Induction of coronary collateral circulation,that is,therapeutic angiogenesis,is considered a promising treatment for coronary heart disease.However,coronary collateral growth is a complex process and is related to a variety of factors.Although it has achieved promising outcomes in animal experiments,clinical trials have so far failed to replicate these results.Further studies on the growth mechanisms of coronary collateral circulation are still needed before a feasible clinical treatment strategy becomes available.