Branched-chain amino acids and cardiometabolic diseases / 中华老年医学杂志

ABSTRACT

Elevated levels of circulating branched-chain amino acids(BCAA)increase the risk of cardiometabolic diseases(CMD)and may be a new risk factor for CMD.However, BCAA have been used as dietary supplements to promote health in clinical nutrition and medicine.BCAA are essential amino acids that must be acquired from food sources.Whether BCAA supplements can cause elevated circulating BCAA levels and consequently lead to CMD is still controversial.Recent studies have found that the roles of BCAA may vary under different conditions such as energy excess, energy deficiency and energy balance.This article reviews recent advances in research on BCAA and CMD.