Clinical diagnosis and treatment of non-motor symptoms of multiple system atrophy / 中华神经科杂志

ABSTRACT

Multiple system atrophy (MSA) is a sporadic neurodegenerative disease with insidious onset, and relatively rapid progress in adult. MSA patients may be admitted to different departments of hospital several years before the full manifestation of motor symptoms, because of various non-motor symptoms such as urinary disorders, sexual dysfunction, orthostatic hypotension, psychic symptoms and sleep disorders. This may delay the diagnosis and treatment of MSA. The review is to improve the understanding of the non-motor symptoms of MSA, which may help to reach more accurate diagnosis and better treatment, and improve the quality of life of patients with MSA.