An exploratory analysis of the relationship between paternal age at pregnancy and difficulties symptomatic of specific learning disorders among Japanese undergraduate students / Journal of Rural Medicine
Journal of Rural Medicine
;
: 35-41, 2021.
Article
Dans Anglais
| WPRIM
| ID: wpr-873896
ABSTRACT
Objective:
Causes and risk factors of neurodevelopmental disorders originate in the prenatal and perinatal periods. Several studies have demonstrated a relationship between prenatal and perinatal medical records, including maternal and paternal age at pregnancy, and the neurodevelopmental disorders, especially attention deficit/hyperactivity disorder and autism spectrum disorder. However, previous studies showed an association between specific learning disorders and environmental toxins such as lead and tobacco smoke, but not parental age.Patients andMethods:
This study included 993 university freshmen, and their prenatal and perinatal medical data was collected from maternal and child handbooks. A mental health assessment questionnaire consisting of 24 items covering symptoms associated with neurodevelopmental disorders was administered, corresponding to aspects of attention deficit/hyperactivity disorder, autism spectrum disorder, and learning disorders. The relationship between prenatal and perinatal medical data and questionnaire results was statistically analyzed.Results:
The number of available records was 881 (88.7%). Using Spearman’s rank correlation coefficient analysis and trend analysis, a weak but statistically significant relationship was confirmed between paternal age at pregnancy and the score for learning disorder difficulties.Conclusion:
Error accumulation in meiosis during spermatogenesis may be one of the risk factors of learning disorders.
Recherche sur Google
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Facteurs de risque
langue:
Anglais
Texte intégral:
Journal of Rural Medicine
Année:
2021
Type:
Article
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