Association Between Non-erosive Reflux Disease and High Risk of Obstructive Sleep Apnea in Korean Population
Journal of Neurogastroenterology and Motility
;
: 197-204, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-87486
ABSTRACT
BACKGROUND/AIMS:
Obstructive sleep apnea is becoming more important in gastroesophageal reflux disease (GERD) patients. This study investigated the prevalence of high risk for obstructive sleep apnea in GERD patients in comparison with that in healthy controls using the Berlin Questionnaire. We also investigated the risk factors for obstructive sleep apnea in GERD patients.METHODS:
We enrolled 1,007subjects:
776 healthy controls, 115 individuals with erosive reflux disease, and 116 with non-erosive reflux disease. GERD was diagnosed and classified using endoscopy and a reflux questionnaire. The Berlin Questionnaire was used to evaluate obstructive sleep apnea.RESULTS:
More patients in the GERD group (28.2%) had higher risk for obstructive sleep apnea than healthy controls (20.4%, P = 0.036). More patients with non-erosive disease (32.8%) had higher risk for obstructive sleep apnea (OSA) than patients with erosive disease (20.9%) and controls (20.4%, P = 0.010). On multivariate analysis, non-erosive disease was a high risk factor for obstructive sleep apnea (odds ratio [OR], 1.82; P = 0.011). Age > or = 55 years (OR, 1.83; P or = 25 kg/m2) (OR, 2.76; P or = 55, and a high BMI are associated with high risk for OSA.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Berlin
/
Reflux gastro-oesophagien
/
Indice de masse corporelle
/
Prévalence
/
Analyse multifactorielle
/
Enquêtes et questionnaires
/
Facteurs de risque
/
Syndrome d'apnées obstructives du sommeil
/
Endoscopie
/
Oesophagite
Type d'étude:
Etude d'étiologie
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Humains
Pays comme sujet:
Europe
langue:
Anglais
Texte intégral:
Journal of Neurogastroenterology and Motility
Année:
2014
Type:
Article
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