Choroidal Detachment in a Patient with Myelodysplastic Syndrome

ABSTRACT

PURPOSE: After myelodysplastic syndrome is transformed to acute leukemia, the patient condition worsens rapidly. The authors experienced a case of choroidal detachment in a patient with myelodysplastic syndrome and report this case with literature review. METHODS: A 59-year-old man with myelodysplastic syndrome was admitted because of systemic illness. After examination, he was diagnosed with acute leukemia transformation. During admission, he experienced visual acuity decrease in the right eye. Ophthalmic examination showed annular choroidal detachment, exudative retinal detachment, and narrow anterior chamber angle. Orbital CT showed anterior rotation of the lens-iris diaphragm, thickened choroids, and slightly enhanced ocular soft tissue. RESULTS: Despite medical treatment including carbonic anhydrase inhibitor for about 2 weeks, the ophthalmic finding was not quite subsided, so surgical treatment was arranged. However, the systemic illness aggrevated abruptly, and the patient died about 1 month after medical treatment.