Research progress of new vaccine adjuvants / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 78-87, 2021.
Article
Dans Chinois
| WPRIM
| ID: wpr-878544
ABSTRACT
In recent years, the development of new vaccines such as nucleic acid vaccines, genetically engineered vaccines, and synthetic peptide vaccines has achieved rapid development. However, compared with traditional inactivated or live vaccines, these vaccines often have problems such as poor immunogenicity. Therefore, an adjuvant is needed to enhance its effect, and adjuvants have proven to be a key component in vaccines. There are many types of adjuvants, while currently no unified standard for the classification. At present, the most commonly used adjuvants are Aluminum adjuvant and Freund's adjuvant, but new generation vaccines will probably need new generation adjuvants. Thus, this review aims to showcase the current status of immune adjuvants, with the focus on immunomodulatory molecular adjuvant, antigen delivery adjuvant and compound adjuvant. This review provides new insights for the development of novel vaccine adjuvants.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Vaccins
/
Adjuvants immunologiques
/
Adjuvant Freund
/
Vaccins sous-unitaires
langue:
Chinois
Texte intégral:
Chinese Journal of Biotechnology
Année:
2021
Type:
Article
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