Progress in genetic research on tooth agenesis associated with Wnt/beta-catenin signaling pathway / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 506-509, 2021.
Article
Dans Chinois
| WPRIM
| ID: wpr-879615
ABSTRACT
Tooth agenesis is the most common form of congenital craniofacial dysplasia seen in stomatology clinics, which may be caused by genetic and/or environmental factors. Tooth development is regulated by a series of signaling pathways, and variants in any of these strictly balanced signaling cascades can result in tooth agenesis and/or other oral defects. Notably, variants of genes of the Wnt/beta-catenin signaling pathway are important cause for both non-syndromic and syndromic tooth agenesis. This article has provided a review for the molecular genetics of tooth agenesis associated with Wnt/beta-catenin signaling pathway, which may shed lights on the etiology and molecular mechanism of this disease.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Dent
/
Recherche génétique
/
Protéines de type Wingless
/
Voie de signalisation Wnt
/
Anodontie
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Medical Genetics
Année:
2021
Type:
Article
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