Guilu Erxian Glue () Inhibits Chemotherapy-Induced Bone Marrow Hematopoietic Stem Cell Senescence in Mice May via p16 / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 819-824, 2020.
Article
Dans Anglais
| WPRIM
| ID: wpr-880540
ABSTRACT
OBJECTIVE@#To evaluate the effect of Guilu Erxian Glue (, GEG) on cyclophosphamide (CTX)-induced bone marrow hematopoietic stem cells (HSCs) senescence in mice and explore the underlying mechanism.@*METHODS@#The H@*RESULTS@#Compared with the model group, GEG increased cell viability as well as proliferation (P<0.05 or P<0.01) and reduced β -gal expression. Furthermore, GEG significantly decreased the expressions of p16@*CONCLUSION@#GEG can alleviate CTX-induced HSCs senescence in mice, and the p16
Texte intégral:
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Indice:
WPRIM (Pacifique occidental)
langue:
Anglais
Texte intégral:
Chinese journal of integrative medicine
Année:
2020
Type:
Article
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