Research advances in add-on treatment for negative symptoms and cognitive dysfunction in schizophrenia / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1457-1463, 2020.
Article
Dans Anglais
| WPRIM
| ID: wpr-880607
ABSTRACT
Antipsychotic medication is the primary treatment for schizophrenia, which is effective on ameliorating positive symptoms and can reduce the risk of recurrence, but it has limited efficacy for negative symptoms and cognitive dysfunction. The negative symptoms and cognitive dysfunction seriously affects the life quality and social function for the patients with schizophrenia. Currently, there is plenty evidence that antipsychotic drugs combined with adjuvant therapy drugs can effectively improve the negative symptoms and cognitive dysfunction. These drugs include anti-oxidants, nicotinic acetylcholine receptors and neuro-inflammatory drugs (anti-inflammatory drugs, minocycline), which show potential clinical effects.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Schizophrénie
/
Neuroleptiques
/
Dysfonctionnement cognitif
/
Anti-inflammatoires
/
Minocycline
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of Central South University(Medical Sciences)
Année:
2020
Type:
Article
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