Progress in systemic therapy for triple-negative breast cancer / 医学前沿
Frontiers of Medicine
;
(4): 1-10, 2021.
Article
Dans Anglais
| WPRIM
| ID: wpr-880946
ABSTRACT
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with a heterogeneous genetic profile. Chemotherapy exhibits substantial activity in a small subset of these patients. Drug resistance is inevitable. Major progress has been made in the genetic analysis of TNBC to identify novel targets and increase the precision of therapeutic intervention. Such progress has translated into major advances in treatment strategies, including modified chemotherapy approaches, immune checkpoint inhibitors, and targeted therapeutic drugs. All of these strategies have been evaluated in clinical trials. Nevertheless, patient selection remains a considerable challenge in clinical practice.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Thérapie moléculaire ciblée
/
Tumeurs du sein triple-négatives
/
Immunothérapie
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Frontiers of Medicine
Année:
2021
Type:
Article
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