The relationship between genetic factors and plasma lipids in Vietnamese living in rural areas
Journal of Preventive Medicine
;
: 13-17, 2008.
Article
Dans Vietnamien
| WPRIM
| ID: wpr-882
ABSTRACT
Background:
Plasma lipids are affected not only by dietary intake and life style but also by genetic factor.Objective:
To discover the relationship between plasma lipids and the presence of LPL S447X and PAF-AH V279F in the bodies of rural Vietnamese population. Subject andMethod:
One hundred and ninety three subjects were randomly selected from rural areas in Ho Chi Minh city. The presence of LPL S447X and PAF-AHV279F polymorphism was determined using an Invader assay, and the plasma lipid levels were measured by an enzymatic method. A profile regarding the dietary intake was also made for each subject. Result andConclusion:
The frequency of LPL 447SX/XX (12.2%) polymorphism, PAF-AH Val279Phe mutation allele frequency (5.4%) in the Vietnamese was closely similar to that of other Asian populations. LPL447X polymorphism was found to be significantly associated with a higher HDL-C level in comparison to LPL 447S. LPL S447X affects plasma HDL-C and TG concentration in Vietnamese rural population.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Zones Rurales
langue:
Vietnamien
Texte intégral:
Journal of Preventive Medicine
Année:
2008
Type:
Article
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