Research Progress of Discoidin Domain Receptor 1 in Breast Cancer and Other Malignant Tumors / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 634-641, 2021.
Article
Dans Chinois
| WPRIM
| ID: wpr-887905
ABSTRACT
Discoidin domain receptor 1(DDR1)is a critical member of the receptor tyrosine kinase family.It may be related to tumor invasion and metastasis,and the abnormal activation of DDR1 can lead to the occurrence and development of malignant tumors,inflammation,and fibrosis.DDR1 are involved in cell adhesion,migration,proliferation,secretion of cytokines,and remodeling of extracellular matrix,thus playing a critical role in various pathophysiological processes of the human body.In this review,we demonstrate the research progress of DDR1 in breast cancer and other malignant tumors,in order to provide a new theoretical basis for the prevention and treatment of breast cancer and other tumors.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Fibrose
/
Tumeurs du sein
/
Adhérence cellulaire
/
Récepteurs à activité tyrosine kinase
/
Récepteur-1 à domaine discoïdine
Limites du sujet:
Femelle
/
Humains
langue:
Chinois
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2021
Type:
Article
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