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Review of chemical constituents,pharmacological effects and clinical applications of Danggui Buxue Decoction and prediction and analysis of its Q-markers / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 2677-2685, 2021.
Article Dans Chinois | WPRIM | ID: wpr-887937
ABSTRACT
Danggui Buxue Decoction is a classic prescription of Qi and blood tonification, which is mainly applied in treating fatigue, internal damage Qi weakness, blood deficiency, and outward going of floating Yang. Modern pharmacology shows that it can promote hematopoiesis, regulate immunity, and protect heart and cerebral vessels. The prescription, often used for the treatment of anemia and other diseases in clinic, is composed of Astragali Radix and Angelicae Sinensis Radix at a dosage ratio of 5∶1. It is a modern compound prescription for invigorating Qi and generating blood. Based on the review of the chemical constituents, pharmacological effects, and clinical applications of Danggui Buxue Decoction, its Q-marker was predicted and analyzed according to the "five principles" of Chinese medicine Q-marker--quality transmissibility and traceability, ingredient specificity, component validity, component measurabi-lity, and formula compatibility environment. The results suggested that calycosin, calycosin-7-O-β-D-glucoside, formononetin, ononin, astragaloside A, ferulic acid, and ligustilide could be used as Q-markers of Danggui Buxue Decoction, which provides reference for establishing the quality system of Danggui Buxue Decoction.
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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Médicaments issus de plantes chinoises / Racines de plante / Astragalus Type d'étude: Étude pronostique langue: Chinois Texte intégral: China Journal of Chinese Materia Medica Année: 2021 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Médicaments issus de plantes chinoises / Racines de plante / Astragalus Type d'étude: Étude pronostique langue: Chinois Texte intégral: China Journal of Chinese Materia Medica Année: 2021 Type: Article