New oligomeric neolignans from the leaves of Magnolia officinalis var. biloba / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 491-499, 2021.
Article
Dans Anglais
| WPRIM
| ID: wpr-888777
ABSTRACT
Six new oligomeric neolignans including two trimeric neolignans (1 and 2) and four dimeric neolignans (3-6) were isolated from the leaves of Magnolia officinalis var. biloba. Their structures were determined based on HR-ESIMS and NMR data, as well as electronic circular dichroism (ECD) calculations. Compound 1 is formed from two obovatol moieties directly linked to an aromatic ring of the remaining obovatol moiety, which is an unprecedented type of linkage between monomers. All isolates were assessed for their inhibitory effects on NO production in LPS-stimulated RAW 264.7 macrophage cells. Compounds 1 and 3 showed significantly inhibitory activities with IC
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Extraits de plantes
/
Structure moléculaire
/
Lignanes
/
Feuilles de plante
/
Magnolia
/
Composés phytochimiques
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2021
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS