Germacranolide sesquiterpenes from Carpesium cernuum and their anti-leukemia activity / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 528-535, 2021.
Article
Dans Anglais
| WPRIM
| ID: wpr-888781
ABSTRACT
In this study, three new germacranolide sesquiterpenes (1-3), together with six related known analogues (4-9) were isolated from the whole plant of Carpesium cernuum. Their structures were established by a combination of extensive NMR spectroscopic analysis, HR-ESIMS data, and ECD calculations. The anti-leukemia activities of all compounds towards three cell lines (HEL, KG-1a, and K562) were evaluated in vitro. Compounds 1-3 exhibited moderate cytotoxicity with IC
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Tests de criblage d'agents antitumoraux
/
Asteraceae
/
Cellules K562
/
Sesquiterpènes de type germacrane
/
Composés phytochimiques
/
Antinéoplasiques d'origine végétale
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2021
Type:
Article
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