Identification and characterization of a novel elastase inhibitor from Hirudinaria manillensis / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
;
(6): 540-544, 2021.
Article
Dans Anglais
| WPRIM
| ID: wpr-888783
ABSTRACT
A large number of protease inhibitors have been found from leeches, which are essential in various physiological and biological processes. In the curret study, a novel elastase inhibitor was purified and characterized from the leech of Hirudinaria manillensis, which was named HMEI-A. Primary structure analysis showed that HMEI-A belonged to a new family of proteins. HMEI-A exerted inhibitory effects on elastase and showed potent abilities to inhibit elastase with an inhibition constant (K
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Inhibiteurs de protéases
/
Pancreatic elastase
/
Protéines
/
Séquence d'acides aminés
/
Sangsues
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2021
Type:
Article
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